Dietary supplement CLA (conjugated linoleic acid) is an isomer of linoleic acid, belonging to the essential polyunsaturated fatty acids from the Omega-6 group. In the digestive tract of ruminants, due to the bacterial flora, linoleic acid is converted into conjugated linoleic acid (CLA), which, when used in humans, strongly reduces adipose tissue through a number of different cellular mechanisms. The different configuration of bonds in the CLA molecule means that, unlike linoleic acid, it inhibits the synthesis of pro-inflammatory and pro-growth prostaglandins, i.e. tissue hormones responsible for the development of fat cells. A large share of CLA in the diet prevents the development of adipose tissue and existing fat cells (not hormonally stimulated) are self-destructing. CLA stimulates the growth of muscle tissue, thanks to which it facilitates the burning of unnecessary calories and intensifies thermogenesis processes in the body. In addition, CLA inhibits the activity of lipoprotein lipase, which, on the surface of fat cells, "catches" fatty acids used for the synthesis of spare fat. Conjugated linoleic acid also has an immunostimulating and antioxidant effect. CLA permanently changes the proportion of tissues in the human body (in favor of muscle tissue) and has a number of health-promoting properties. CLA permanently changes the proportion of tissues in the human body in favor of muscle tissue.
 
One-year CLA supplementation, with no change in caloric intake or exercise, resulted in a 9% decrease in body fat in healthy obese individuals with a 1.8% increase in lean body mass (American Journal of Clinical Nutrition, Vol. 79, No. 6, 1118-1125, June 2004) - the results speak for themselves